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Active (not recruiting) Phase 2 2025-521673-14-00

An Open-label Multicenter Rollover Study to Provide Continued Treatment to Participants Previously Enrolled in a RVU120 Clinical Study

Phase 2 – studying effectiveness and dosage
Conditions: Relapsed / Refractory Metastatic or Advanced Solid Tumors Myelofibrosis Relapsed or Refractory High-Risk Myelodysplastic Syndrome Acute Myeloid Leukemia with or without NPM1 Mutation

Sponsor: Ryvu Therapeutics S.A.

trial.available_in: БГ
Overview
Trial status: Authorised Time from the first administration of RVU120-based treatment in the parent study until discontinuation of RVU120-based treatment for any reason in the rollover study Incidence and severity of adverse events (AEs) and serious adverse events (SAEs)
Description
Time from the first administration of RVU120-based treatment in the parent study until discontinuation of RVU120-based treatment for any reason in the rollover study
Who can participate
Age group: 65+ years, 18-64 years Gender: Female, Male Target enrollment: 29 participants
Interventions
Jakavi 5 mg tablets
Drug
Jakavi 15 mg tablets
Drug
Jakavi 15 mg tablets
Drug
VENETOCLAX
Drug
SEL120 monohydrochloride
Drug
VENETOCLAX
Drug
Jakavi 20 mg tablets
Drug
Jakavi 15 mg tablets
Drug
Jakavi 5 mg tablets
Drug
Jakavi 20 mg tablets
Drug
Jakavi 5 mg tablets
Drug
VENETOCLAX
Drug
SEL120 monohydrochloride
Drug
Jakavi 20 mg tablets
Drug
Locations 4
France (1)
Italy (1)
Poland (1)
Spain (1)
Technical details
Status
Active (not recruiting)
Phase
Phase 2
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Healthy volunteers
No
Start date
27.08.2025
Registry ID
2025-521673-14-00
Source
euclinicaltrials.eu
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