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Активно (без набиране) Не е приложимо NCT02841618

The Healthy Cookie Study: Understanding How Healthy Cookies Affect Fat in the Blood,

Не е приложима фаза (напр. обсервационно)
Заболявания: Healthy Adults

Спонсор: Ohio State University

Налично на: БГ
Обобщение
The purpose of this study is to understand how consuming healthy cookies every day for two weeks will affect different types of fat in the blood. Specifically, the overall goal of this study is to find out if the healthy cookies can increase a polyunsaturated fat called linoleic acid in plasma, red blood cells and white blood cells.
Описание
Overall, linoleic acid has many health benefits including altering body composition and energy metabolism, possibly through its impact on cardiolipin. It is therefore imperative to develop foods products that allow for Americans to easily increase their intake of linoleic acid. It's also important to understand the mechanism in which linoleic acid exerts these positive health effects, particularly in states of muscle mass and quality loss associated with mitochondria dysfunction. The investigators plan to test the central hypothesis and accomplish the overall objective of this research by pursuing the following three specific aims Aim 1: To determine the extent to which cookies, made with grapeseed oil , increase linoleic acid in plasma, red blood cells (RBCs), and peripheral blood mononuclear cells (PBMCs) fraction of blood after two weeks consumption Aim 2: To determine the extent to which cookies, made with grapeseed oil, increase cardiolipin and linoleic acid content of cardiolipin in PBMCs after two weeks of consumption Aim 3: To determine and compare the acceptability of consuming cookies made with grapeseed oil or high oleic safflower oil every day for two weeks
Кой може да участва
Inclusion Criteria: * Nonsmokers Exclusion Criteria: * Current or previous diagnosis of diabetes, heart (including stroke or heart attack), kidney, liver or circulatory diseases and/or current treatment for cancer. * Gastrointestinal diseases or disorders (including pancreatic) or gastric bypass surgery * Food Allergy or Intolerance \& Bee allergy * Any dietary restriction where consumption of these healthy cookies or any ingredient would be contraindicated * Use of medications where consuming the healthy cookies would be contraindicated * Use of supplements/oils high in linoleic acid in the past 4 weeks prior to enrolling * Pregnancy
Интервенции
High Linoleic Acid Healthy Cookies
OTHER
High Oleic Acid Healthy Cookies
OTHER
Места на провеждане 1
САЩ (1)
The Ohio State University Human Nutrition Laboratory
Columbus , Ohio
Технически детайли
Статус
Активно (без набиране)
Фаза
Не е приложимо
Вид изследване
INTERVENTIONAL
Пол
Мъже и жени
Минимална възраст
18 Years
Максимална възраст
80 Years
Здрави доброволци
Не
Начална дата
01.01.2016
Крайна дата
01.12.2026
Регистрационен номер
NCT02841618
Източник
clinicaltrials.gov
Запитване за медицински туризъм

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