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Active (not recruiting) Not applicable NCT05256940

Motivational Interviewing to Address Suicidal Ideation for Veterans at High Risk for Suicide

No applicable phase (e.g. observational)
Conditions: Suicide, Attempted Suicidal Ideation

Sponsor: VA Office of Research and Development

trial.available_in: БГ
Overview
The purpose of this project is to conduct a randomized control trial with 470 Veterans to examine the impact of a revised version of Motivational Interviewing to Address Suicidal Ideation (MI-SI-R) on risk for suicide attempts and suicidal ideation when compared to high quality usual care.
Description
Research suggests that treatments to reduce suicidal behavior may need to focus on both the motivation to live and the motivation to die to obtain optimal effects. The PI developed a revised version of Motivational Interviewing to Address Suicidal Ideation (MI-SI-R) to help Veterans resolve ambivalence about living by increasing the motivation to live, that consists of three sessions delivered in-person, virtually, or by telephone. Enhanced usual care (EUC) for high-risk Veterans includes safety plans administered or reviewed by research therapists, care coordination, and access to a 24-hour crisis hotline. In a preliminary randomized controlled trial (RCT) in psychiatrically hospitalized Veterans, MI-SI-R plus EUC was associated with 50% fewer suicide attempts and 41% lower likelihood of suicidal ideation compared to EUC alone. The investigators are proposing an RCT comparing MI-SI-R plus EUC (MI-SI-R+EUC) to EUC alone in a sample of 470 high-risk Veterans with recent suicidal crises from three VHA Medical Centers, with "high-risk" defined as a suicide attempt within a month or suicidal ideation \> 5 on the Beck Scale for Suicidal Ideation. Half (n = 235) will be randomized to MI-SI-R+EUC (three sessions in-person, via Video Connect, or telephone) and the remaining participants (n = 235) will receive EUC alone. All participants will be asked to complete telephone follow-up assessments at 1, 3, 6, and 12-months after randomization. This will allow the investigators to determine the efficacy of MI-SI-R+EUC in reducing risk for suicide attempts (Aim 1) and reducing overall suicidal ideation (Aim 2) when compared to EUC alone.
Who can participate
Inclusion Criteria: * Veteran status, * admitted to an inpatient unit, referred by a suicide prevention coordinator, or identified as high-risk via data extraction, * age 18 and over, * English speaking and reading, and * ability to understand the study and provide informed consent, * high-risk status confirmed by suicide attempt within a month on the Columbia- Suicide Severity Rating Scale or a score \> 5 on the Scale for Suicidal Ideation Exclusion Criteria: * current psychosis, * active mania, * dementia, * impaired decision making capacity, and * institutionalization due to hospitalization in a non-VA facility, jail, or prison.
Interventions
Motivational Interviewing to Address Suicidal Ideation- Revised (MI-SI-R)
BEHAVIORAL
Enhanced usual care (EUC)
OTHER
Locations 3
United States (3)
VA Finger Lakes Healthcare System, Canandaigua, NY
Canandaigua , New York
Ralph H. Johnson VA Medical Center, Charleston, SC
Charleston , South Carolina
VA Portland Health Care System, Portland, OR
Portland , Oregon
Technical details
Status
Active (not recruiting)
Phase
Not applicable
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Healthy volunteers
No
Start date
30.11.2022
Completion date
29.06.2027
Registry ID
NCT05256940
Source
clinicaltrials.gov
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