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Само по покана Не е приложимо NCT05461157

Preoperative Silicone Ointment and Wound Healing

Не е приложима фаза (напр. обсервационно)
Заболявания: Wound Heal Scar Scar, Hypertrophic Keloid Keloid Scar Following Surgery Surgical Incision

Спонсор: Yale University

Налично на: БГ
Обобщение
Optimal scar healing is of great importance to patients, especially following surgery of the head and neck. This study evaluates the effectiveness of preoperative silicone ointment in wound healing in head and neck surgeries.
Описание
Following surgical procedures, the formation of hypertrophic scars and keloids affects patients' well-being, including quality of life and mental/psychological health. Scars in certain areas, including the face, neck, ears, and upper chest and back, are especially likely to develop abnormally. Due to these adverse outcomes, patients often request products and procedures that will improve the appearance of scars. Few studies have addressed preoperative measures that can improve scar healing. Surgeons often recommend that patients apply moisturizing ointments to the area of the incision prior to surgery; however, this is based on clinical consensus and is not evidence-based. Silicone products are understood to promote hydration of the skin and are considered first-line prophylactic and treatment therapy for abnormal scars (hypertrophic scars and keloids) when used after a surgery or injury. This study seeks to evaluate preoperative application of silicone ointment and its effect on surgical scar healing. The success of surgical scar healing will be determined by researcher and participant ratings on validated scar assessment scales. The secondary objective of this study is to evaluate the effect of preoperative application of silicone ointment on postoperative wound complications.
Кой може да участва
Inclusion Criteria: * Scheduled to undergo non-emergent surgery of the head and/or neck for a benign (non-cancerous) condition * Able to comply with all study procedures for the duration of the study * Provision of signed and dated informed consent form Exclusion Criteria: * Current use of products intended to improve scar healing (silicone or otherwise); skincare products not specifically marketed for scar healing are acceptable * Known allergic reactions to components of the silicone ointment * Dermatologic conditions that disrupt the integrity of the skin, e.g. severe acne, psoriasis * Need for tracheostomy postoperatively * Have any form of active malignancy at the time of surgery * Have a history of radiation involving the surgical site * Prior surgery involving all or part of the planned surgical incision * Current use of chronic steroids or other immunosuppressive medications * Lack of decision-making capacity * Not fluent in English
Интервенции
Preoperative silicone ointment
DEVICE
Preoperative placebo ointment
OTHER
Места на провеждане 1
САЩ (1)
Yale New Haven Hospital
New Haven , Connecticut
Технически детайли
Статус
Само по покана
Фаза
Не е приложимо
Вид изследване
INTERVENTIONAL
Пол
Мъже и жени
Минимална възраст
18 Years
Здрави доброволци
Не
Начална дата
14.11.2022
Крайна дата
01.07.2027
Регистрационен номер
NCT05461157
Източник
clinicaltrials.gov
Запитване за медицински туризъм

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