Език: EN EN
← Назад към резултатите
Набира участници Фаза 3 NCT06615479

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

Фаза 3 – широко изпитване преди одобрение
Заболявания: Relapsed or Refractory Multiple Myeloma (RRMM)

Спонсор: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Налично на: БГ
Обобщение
The purpose of this study is to compare the efficacy and safety of arlo-cel (BMS-986393) versus standard regimens in adult participants with Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma.
Кой може да участва
Inclusion Criteria * Participants must have relapsed or refractory multiple myeloma (RRMM). * Participants must have received at least 1 but no greater than 3 prior multiple myeloma (MM) regimens which may include a proteasome inhibitor (PI), an immunomodulatory drug (IMiD), and an anti-CD38 monoclonal antibody and have prior exposure to lenalidomide. * Participants must have a documented diagnosis of MM as per International Myeloma Working Group Criteria. * Participants must have measurable disease during screening. * Participants must have adequate organ function. * Participants must have an Eastern Cooperative Oncology group performance status 0 or 1. Exclusion Criteria * Participants must not have known active or history of central nervous system (CNS) involvement of Multiple Myeloma (MM). * Participants must not have solitary plasmacytomas or non-secretory myeloma without other evidence of measurable disease. * Participants must not need urgent treatment due to rapidly progressing MM. * Other protocol-defined Inclusion/Exclusion criteria apply.
Места на провеждане 27
Argentina (1)
Hospital Italiano de Buenos Aires
ABB , Buenos Aires F.D.
Natalia Schutz, Site 0122
Австралия (1)
Royal Prince Alfred Hospital
Camperdown , New South Wales
Joy Ho, Site 0142
Белгия (1)
Antwerp University Hospital
Edegem , Antwerpen
Sebastien Anguille, Site 0220
Бразилия (1)
Local Institution - 0012
Nova Lima , Minas Gerais
NOT_YET_RECRUITING
Канада (1)
Arthur J.E. Child Comprehensive Cancer Centre
Calgary , Alberta
Nizar Bahlis, Site 0069
Чехия (1)
Fakultní nemocnice Brno Bohunice
Brno , Brno-město
Ludek Pour, Site 0094
Дания (1)
Rigshospitalet
Copenhagen , Capital Region
Anne Mylin, Site 0019
Финландия (1)
Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus)
Helsinki , Uusimaa
Mikko Keranen, Site 0026
Франция (1)
Hopital Claude Huriez - CHU de Lille
Lille , Nord
Salomon Manier, Site 0081
Гърция (1)
University Hospital of Patras
Pátrai , Achaḯa
Alexandros Spyridonidis, Site 0111
Унгария (1)
Debreceni Egyetem Klinikai Kozpont
Debrecen , Hajdú-Bihar
Arpad Illes, Site 0124
Израел (1)
Sheba Medical Center
Ramat Gan , Central District
Hila Magen, Site 0112
Италия (1)
Fondazione IRCCS Istituto Nazionale dei Tumori
Milan , Lombardy
Paolo Corradini, Site 0107
Япония (1)
Nagoya City University Hospital
Nagoya , Aichi-ken
Masaki Ri, Site 0098
Нидерландия (1)
Radboudumc
Nijmegen , Gelderland
Elizabeth De Kort, Site 0176
Норвегия (1)
Sykehusapoteket Ull
Oslo
Ingerid Abrahamsen, Site 0016
Полша (1)
Centrum Onkologii Ziemi Lubelskiej
Lublin , Lublin Voivodeship
Wojciech Legiec, Site 0092
Румъния (1)
Fundeni Clinical Institute
Bucharest , Bucharest
Alina Tanase, Site 0173
Saudi Arabia (1)
Local Institution - 0178
Riyadh
NOT_YET_RECRUITING
Сингапур (1)
National University Hospital
Singapore , Central Singapore
Esther Chan, Site 0180
Южна Корея (1)
Seoul National University Hospital
Seoul , Seoul-teukbyeolsi [Seoul]
YOUNGIL KOH, Site 0147
Испания (1)
CHUS - Hospital Clinico Universitario
Santiago de Compostela , A Coruña [La Coruña]
Marta Sonia GOnzalez Perez, Site 0136
Швеция (1)
Sahlgrenska Universitetssjukhuset
Gothenburg , Västra Götalands Län [se-14]
Markus Hansson, Site 0025
Taiwan (1)
National Taiwan University Cancer Center (NTUCC)
Taipei City , Taipei
Bor-Sheng Ko, Site 0150
Турция (1)
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi
Ankara
Fevzi Altuntas, Site 0170
Великобритания (1)
Addenbrooke's Hospital
Cambridge , Cambridgeshire
Faisal Basheer, Site 0182
САЩ (1)
University of Alabama at Birmingham
Birmingham , Alabama
Susan Bal, Site 0071
Технически детайли
Статус
Набира участници
Фаза
Фаза 3
Вид изследване
INTERVENTIONAL
Пол
Мъже и жени
Минимална възраст
18 Years
Здрави доброволци
Не
Начална дата
12.03.2025
Крайна дата
22.06.2032
Регистрационен номер
NCT06615479
Източник
anzctr
Запитване за медицински туризъм

Информацията е извлечена автоматично от ClinicalTrials.gov. Консултирайте се с вашия лекар преди да предприемете действия.