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Active (not recruiting) NCT06747572

Polycystic Kidney Disease 1 (PKD1) Gene Variant Groups in Autosomal Dominant Polycystic Kidney Disease

Conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Sponsor: Vertex Pharmaceuticals Incorporated

trial.available_in: БГ
Overview
The purpose of this study is to estimate the prevalence, demographic, and clinical characteristics of PKD1/2 gene variant groups in the ADPKD population.
Who can participate
Key Inclusion Criteria: * Estimated glomerular filtration rate (eGFR) greater than or equal to (≥) 30 milliliter per minute (mL/min)/1.73 m\^2 * Willing and able to comply with scheduled visits and other study procedures * A pre-existing diagnosis of ADPKD as defined in the protocol Key Exclusion Criteria: * History of kidney disease other than ADPKD that in the opinion of the investigator would independently impact the natural history of ADPKD * History of solid organ or bone marrow transplantation or nephrectomy * Ongoing renal replacement therapy or planning to start renal replacement therapy less than or equal to (≤)12 months from the Genotyping Visit in Part A Other protocol defined Inclusion/Exclusion criteria will apply.
Locations 45
Belgium (2)
Universite Catholique de Louvain, Cliniques universitaires Saint-Luc (UCLouvain)
Brussels
Universitaire Ziekenhuizen Leuven
Leuven
Canada (2)
St. Joseph's Healthcare - Hamilton
Hamilton
MUHC - Montreal Children's Hospital
Montreal
France (2)
Hopital de la Cavale Blanche
Brest
Necker Hospital
Paris
Germany (2)
Charité - Klinik für Nephrologie und Intensivmedizin der
Berlin
Universitaetsklinik Koeln Department II of Internal Medicine
Cologne
Netherlands (2)
UMCG - Nephrology
Groningen
Erasmus Medisch Centrum - Nephrology
Rotterdam
Puerto Rico (1)
FDI Clinical Research - San Juan
San Juan
Spain (1)
Hospital Fundacion Jimenez Diaz
Madrid
United Kingdom (6)
Queen Elizabeth Hospital Birmingham
Birmingham
King's College Hospital
London
Royal Free NHS Trust
London
St Georges University Hospitals NHS Foundation Trust
London
Newcastle upon Tyne Hospitals NHS Foundation Trust - Freeman Hospital - Nephrology
Newcastle upon Tyne
Northern General Hospital
Sheffield
United States (27)
Alabama Kidney Research
Alabaster , Alabama
Emory School of Medicine - Renal Division
Atlanta , Georgia
General Clinical Research Center, University of Maryland Baltimore
Baltimore , Maryland
University of Alabama at Birmingham- Nephrology Research Clinic
Birmingham , Alabama
Tufts Medical Center
Boston , Massachusetts
Beth Israel Deaconess Medical Center - Nephrology
Boston , Massachusetts
UVM Medical Center - 1 South Prospect Street
Burlington , Vermont
UChicago Medicine - Duchossois Center for Advanced Medicine - Nephrology
Chicago , Illinois
Renal Associates, LLC
Columbus , Georgia
Geisinger Clinic
Danville , Pennsylvania
Quest Research Institute
Farmington Hills , Michigan
Nature Coast Clinical Research - Inverness
Inverness , Florida
University of Iowa Health Care Medical Center- Nephrology
Iowa City , Iowa
Mayo Clinic - Jacksonville
Jacksonville , Florida
University of Kansas Medical Center
Kansas City , Kansas
DaVita Clinical Research
Las Vegas , Nevada
Kaiser Permanente - Los Angeles Medical Center
Los Angeles , California
UCLA Division of Nephrology
Los Angeles , California
Nephrology & Hypertension Associates, PC
Middlebury , Connecticut
University of Minnesota -Health Clinical Research Unit
Minneapolis , Minnesota
Nephrology Clinical Trials Center
Nashville , Tennessee
Yale Nephrology Clinical Research Clinic
New Haven , Connecticut
Columbia University Medical Center
New York , New York
Perelman Center for Advanced Medicine - Nephrology
Philadelphia , Pennsylvania
Mayo Clinic - Rochester
Rochester , Minnesota
Helen Diller Medical Center at Parnassus Heights
San Francisco , California
Swedish Center for Comprehensive Care
Seattle , Washington
Technical details
Status
Active (not recruiting)
Study type
OBSERVATIONAL
Sex
Male and female
Minimum age
12 Years
Maximum age
65 Years
Healthy volunteers
No
Start date
19.12.2024
Completion date
31.12.2026
Registry ID
NCT06747572
Source
clinicaltrials.gov
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