Conditions:
Behavior
Stress
Quality of Life
Psychological Wellbeing
Sponsor: German Institute of Human Nutrition
trial.available_in:
БГ
Overview
The behavioral within-subject cross-over design study "CoVa" aims to investigate the effect of a short-term full-body cold-water immersion vs. warm-water immersion control on value-based choice, psychological well-being, and peripheral physiology.
Description
This randomized within-subject cross-over design behavioral study in cognitive neuroscience will employ an acute peripheral physiological intervention, i.e., a 10-minute full-body cold-water (10-16°C) immersion vs. a control condition (10 min @ 30- 36°C water) on two visits separated by approx. 30 days.
Forty eligible female and male participants will be subject to a head-out full-body cold-water immersion or a warm-water condition (control) on two visits. Participants will perform resting-state and task-based non-invasive electrophysiological recordings of the heart, pulse, respiration, skin conductance, and pupil, will undergo thermographic imaging, pre- and post-immersion blood sampling (4 time points), engage in two computer-based decision-making tasks (reinforcement learning task, risk decision-making task), a brief food choice task, and receive a battery of psychometric questionnaires. The visits are separated by approximately 30 days and do not differ in their timeline except for the primary intervention, i.e., cold vs warm-water immersion, and the medical screening on visit 1.
Who can participate
Inclusion Criteria:
* 18-40 years of age
* Consent to participate
* Fluency in German
* Physically and mentally healthy
* BMI 18-30 kg/m2
* Normal day-night rhythm
Exclusion Criteria:
* Raynaud syndrome
* Cold urticaria
* High resting heart rate (\>160 beats per minute)
* Acute infection
* Diagnosed current or former illnesses of
* Brain and mind
* Heart and blood circulation
* Gastrointestinal system
* Endocrine system
* Other serious past or present medical conditions
* Wearing of medical devices (e.g., pacemaker)
* Fear of blood, needles, or phlebotomy
* Allergies to plasters, gels, and other medical equipment
* Allergies to commercially available liquid meals (e.g., shakes, yfood Labs GmbH)
* Recurrent intake of medication which affect metabolism
* Regular nicotine consumption (e.g., vaping, cigarettes)
* Excessive alcohol consumption (\>14 servings/week)
* Recent illegal drug consumption (within 2 weeks prior)
* Strong mental or physical stress
* Excessive exercise (\>2 h high-intensity exercise/day)
* Pregnancy or breastfeeding
* Inability to wear skin-exposing swimwear, e.g., for religious reasons
* Affinity for winter swimming, cryotherapy, breathwork (\>3 times/year)
Interventions
Cold-water immersion
BEHAVIORAL
Warm-water immersion (Control)
BEHAVIORAL
Locations
1
Germany (1)
German Institute of Human Nutrition Potsdam-Rehbruecke