Language: BG BG
← Back to results
Recruiting Not applicable NCT06908447

Cold Water and Decision-Making

No applicable phase (e.g. observational)
Conditions: Behavior Stress Quality of Life Psychological Wellbeing

Sponsor: German Institute of Human Nutrition

trial.available_in: БГ
Overview
The behavioral within-subject cross-over design study "CoVa" aims to investigate the effect of a short-term full-body cold-water immersion vs. warm-water immersion control on value-based choice, psychological well-being, and peripheral physiology.
Description
This randomized within-subject cross-over design behavioral study in cognitive neuroscience will employ an acute peripheral physiological intervention, i.e., a 10-minute full-body cold-water (10-16°C) immersion vs. a control condition (10 min @ 30- 36°C water) on two visits separated by approx. 30 days. Forty eligible female and male participants will be subject to a head-out full-body cold-water immersion or a warm-water condition (control) on two visits. Participants will perform resting-state and task-based non-invasive electrophysiological recordings of the heart, pulse, respiration, skin conductance, and pupil, will undergo thermographic imaging, pre- and post-immersion blood sampling (4 time points), engage in two computer-based decision-making tasks (reinforcement learning task, risk decision-making task), a brief food choice task, and receive a battery of psychometric questionnaires. The visits are separated by approximately 30 days and do not differ in their timeline except for the primary intervention, i.e., cold vs warm-water immersion, and the medical screening on visit 1.
Who can participate
Inclusion Criteria: * 18-40 years of age * Consent to participate * Fluency in German * Physically and mentally healthy * BMI 18-30 kg/m2 * Normal day-night rhythm Exclusion Criteria: * Raynaud syndrome * Cold urticaria * High resting heart rate (\>160 beats per minute) * Acute infection * Diagnosed current or former illnesses of * Brain and mind * Heart and blood circulation * Gastrointestinal system * Endocrine system * Other serious past or present medical conditions * Wearing of medical devices (e.g., pacemaker) * Fear of blood, needles, or phlebotomy * Allergies to plasters, gels, and other medical equipment * Allergies to commercially available liquid meals (e.g., shakes, yfood Labs GmbH) * Recurrent intake of medication which affect metabolism * Regular nicotine consumption (e.g., vaping, cigarettes) * Excessive alcohol consumption (\>14 servings/week) * Recent illegal drug consumption (within 2 weeks prior) * Strong mental or physical stress * Excessive exercise (\>2 h high-intensity exercise/day) * Pregnancy or breastfeeding * Inability to wear skin-exposing swimwear, e.g., for religious reasons * Affinity for winter swimming, cryotherapy, breathwork (\>3 times/year)
Interventions
Cold-water immersion
BEHAVIORAL
Warm-water immersion (Control)
BEHAVIORAL
Locations 1
Germany (1)
German Institute of Human Nutrition Potsdam-Rehbruecke
Nuthetal
Technical details
Status
Recruiting
Phase
Not applicable
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Maximum age
40 Years
Healthy volunteers
No
Start date
28.08.2025
Completion date
31.12.2026
Registry ID
NCT06908447
Source
clinicaltrials.gov
trial.inquiry_btn

Information is automatically extracted from ClinicalTrials.gov. Consult your doctor before taking action.