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Recruiting NCT07054944

Tumor-Lymph Node Mapping

Conditions: Pediatric Solid Tumors Rhabdomyosarcoma Sarcoma Germ Cell Tumor

Sponsor: University of Rochester

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Overview
The purpose of this study is to assess the feasibility and safety of ICG-guided intraoperative lymphography for detecting sentinel lymph nodes (SLN) in pediatric patients with solid tumors who require retroperitoneal lymph node dissection/sampling. This trial is a single-site cross-sectional study. The injection of ICG directly into lymphatics draining the primary tumor will take place at the time of operation after the patient is under anesthesia.
Who can participate
Inclusion Criteria: * Any pediatric patient (under the age of 18 years) being treated at the University of Rochester Medical Center, Department of Surgery. * Diagnosed with pediatric solid tumor * Scheduled to undergo lymph node sampling as part of their clinical management. Exclusion Criteria: * Subjects with a history of iodide allergies. * Inability or unwillingness of research participant or parent/legal guardian to give written informed consent. * Currently pregnant. * Infants under 650 grams. * Patients with extensive prior surgery at the primary site or nodal basin expected to affect the lymphatic drainage.
Interventions
ICG (Indocyanine Green)
DIAGNOSTIC_TEST
Locations 1
United States (1)
University of Rochester Medical Center
Rochester , New York
Technical details
Status
Recruiting
Study type
OBSERVATIONAL
Sex
Male and female
Minimum age
1 Month
Maximum age
17 Years
Healthy volunteers
No
Start date
13.04.2026
Completion date
30.07.2028
Registry ID
NCT07054944
Source
clinicaltrials.gov
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