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Recruiting Phase 1 NCT07089823

A Study of YP05002 in Healthy Participants

Phase 1 – testing safety in a small group of people
Conditions: Weight Management

Sponsor: Yaopharma Co., Ltd.

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Overview
This is a phase I, randomized, double-blind, placebo-controlled, single and multiple ascending dose study to evaluate the safety, tolerability, pharmacokinetics, efficacy, food effect of YP05002 Tablets in healthy participants
Who can participate
Inclusion Criteria: 1. Willing and able to comply with all scheduled visits, treatment plan, laboratory tests, and other study procedures. 2. Healthy male and female participants aged 18-65 years (both inclusive).No restrictions on race. 3. In good health as determined by the Investigator, with no clinically significant findings from medical/psychiatric history, physical examination, 12-lead ECG, vital signs measurements, clinical laboratory evaluations. Exclusion Criteria: 1. Have evidence of any clinically significant active or chronic disease. 2. Histories of using drug that affect drug absorption, distribution, metabolism, or excretion within 14 days or within 5-half-life prior to the first dose (whichever is longer); gastrointestinal disorders with impaired gastric emptying; or prolonged use of medications that directly modulate gastrointestinal motility. 3. Had clinically relevant acute or chronic medical conditions or diseases that would pose a risk to participant's safety or interfere with the study assessments, as determined by the Investigator. 4. Any malignancy (except basal cell carcinoma and squamous cell carcinoma of the skin) in the previous 5 years. 5. Diagnosis of any type of pancreatitis.
Locations 1
Australia (1)
Nucleus Network Melbourne Clinic
Melbourne , Victoria
Technical details
Status
Recruiting
Phase
Phase 1
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Maximum age
65 Years
Healthy volunteers
No
Start date
19.08.2025
Completion date
30.06.2026
Registry ID
NCT07089823
Source
anzctr
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