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Recruiting Phase 2 NCT07150845

Phase 2b Study of EVO756 in Adults With Atopic Dermatitis

Phase 2 – studying effectiveness and dosage
Conditions: Atoptic Dermatitis

Sponsor: Evommune, Inc.

trial.available_in: БГ
Overview
This study will evaluate the efficacy and safety of different doses of EVO756 in adults with moderate to severe atopic dermatitis.
Who can participate
Inclusion Criteria: * Chronic AD that has been present for ≥6 months * Validated-Investigator's Global Assessment score of ≥3 * EASI of ≥16 * BSA of AD involvement of ≥10% Exclusion Criteria: * Any clinically significant abnormality in laboratory evaluations, physical examinations, vital signs, or ECG at Screening * Use of certain medications * Presence of skin comorbidities or other condition(s) that may interfere with study assessments * Significant AD flare, in the opinion of the Investigator, within 4 weeks prior to study entry
Interventions
EVO756
DRUG
EVO756
DRUG
EVO756
DRUG
Placebo control
DRUG
Locations 29
New Zealand (5)
Optimal Clinical Trials
Auckland , NZL
Optimal Clinical Trials
Auckland , NZL
Pacific Clinical Research Network (PCRN) - Christchurch
Christchurch Central City , Christchurch
Clinical Trials NZ Limited
Hamilton , NZL
Momentum Clinical Research Lower Hutt
Lower Hutt , NZL
United States (24)
Great Lakes Research Group, Inc.
Bay City , Michigan
Skin Care Research, LLC
Boca Raton , Florida
Equity Medical
Bowling Green , Kentucky
DOCS Dermatology Clinical Research
Canal Winchester , Ohio
DS Research
Clarksville , Indiana
Driven Research, LLC
Coral Gables , Florida
Empire Dermatology
East Syracuse , New York
Center for Dermatology Clinical Research
Fremont , California
Skin Care Research - Hollywood Dermatology
Hollywood , Florida
Stryde Research
Lewisville , Texas
Metropolis Dermatology - Downtown Los Angeles
Los Angeles , California
International Clinical Research - Murfreesboro
Murfreesboro , Tennessee
Equity Medical
New York , New York
Skin and Beauty Center
Pasadena , California
Saguaro Dermatology
Phoenix , Arizona
Skin Search of Rochester, Inc.
Rochester , New York
Aesthetic and Dermatology Center
Rockville , Maryland
MediSearch Clinical Trials
Saint Joseph , Missouri
Progressive Clinical Research
San Antonio , Texas
Jordan Valley Dermatology Center
South Jordan , Utah
TrueBlue Clinical Research
Tampa , Florida
Revival Research Institute, LLC
Troy , Michigan
Michigan Dermatology Institute
Waterford , Michigan
Wilmington Dermatology Center
Wilmington , North Carolina
Technical details
Status
Recruiting
Phase
Phase 2
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Healthy volunteers
No
Start date
26.08.2025
Completion date
01.07.2026
Registry ID
NCT07150845
Source
clinicaltrials.gov
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