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Active (not recruiting) Phase 2 NCT07162181

Long-Term Safety of Pirtobrutinib in Participants With Previously Treated Types of Blood Cancers

Phase 2 – studying effectiveness and dosage
Conditions: Lymphoma, Non-Hodgkin Leukemia, Lymphocytic, Chronic, B-Cell B-cell Lymphoma

Sponsor: Eli Lilly and Company

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Overview
The purpose of this study is to find out more about the long-term safety of pirtobrutinib in participants with previously treated types of blood cancer. Participants must have chronic lymphocytic leukemia, small lymphocytic lymphoma, or non-Hodgkins lymphoma. The study is open to those who completed the original study - J2N-MC-JZNJ (NCT04849416) and continue to benefit from treatment. Treatment will be given every 12 weeks and this study is expected to last about 5 years.
Who can participate
Inclusion Criteria: * Currently enrolled and active in the originator study, JZNJ. A participant is considered active in the study if they are receiving study intervention * Agree to comply with contraception requirements. Contraceptive use by participants should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies Exclusion Criteria: * Are pregnant, or intend to become pregnant during the study, or within 30 days of last dose of study treatment or to breastfeed during the study or within 1 week of the last dose of study treatment
Interventions
Pirtobrutinib
DRUG
Locations 6
China (6)
Beijing Cancer hospital
Beijing
Sun Yat-sen University Cancer Center
Guangzhou
Harbin Medical University Cancer Hospital
Harbin
Shanghai East Hospital
Shanghai
Blood Institute of the Chinese Academy of Medical science
Tianjin
Union Hospital Tongji Medical College Huazhong University of Science and Technology
Wuhan
Technical details
Status
Active (not recruiting)
Phase
Phase 2
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Healthy volunteers
No
Start date
07.08.2025
Completion date
01.05.2030
Registry ID
NCT07162181
Source
clinicaltrials.gov
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Information is automatically extracted from ClinicalTrials.gov. Consult your doctor before taking action.