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Recruiting Not applicable NCT07312123

A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome

No applicable phase (e.g. observational)
Conditions: Carpal Tunnel Syndrome

Sponsor: Hospital Universiti Sains Malaysia

trial.available_in: БГ
Overview
Carpal Tunnel Syndrome (CTS) is a common condition that causes numbness, tingling, pain, and weakness in the hand due to compression of the median nerve at the wrist. It can affect daily activities, work performance, and quality of life. While surgery is effective in severe cases, many patients with mild to moderate CTS are initially treated with non-surgical options such as splinting and medications. However, the effectiveness of oral supplements for CTS remains uncertain. This clinical study aims to evaluate whether an oral combination of alpha-lipoic acid, Vitamin E, and Vitamin B complex can safely reduce symptoms and improve hand function in patients with Carpal Tunnel Syndrome. These supplements are believed to have antioxidant, anti-inflammatory, and nerve-protective properties, which may help reduce nerve irritation and improve nerve recovery. Participants in this study will be randomly assigned to receive either the oral supplement combination or a comparator treatment. The study is single-blinded, meaning participants will not know which treatment they are receiving. Symptoms such as pain, numbness, and hand function will be assessed over a defined follow-up period using clinical evaluation and standardized questionnaires. The main hypothesis of this study is that patients receiving the oral combination of alpha-lipoic acid, Vitamin E, and Vitamin B will experience greater improvement in symptoms and functional outcomes compared to those who do not receive the combination, without significant side effects. The results of this study may help determine whether this oral supplement combination can be used as an effective and safe conservative treatment option for patients with Carpal Tunnel Syndrome, potentially reducing the need for invasive procedures.
Who can participate
Inclusion Criteria: * Age more than 18 years old * Subjects with symptoms and physical examination of CTS * Patients with CTS going for CT release Exclusion Criteria: * Pregnant or breast-feeding women * Patients with history of trauma in the dominant hand
Interventions
Alpha-Lipoic Acid, Vitamin E, and Vitamin B Complex
DIETARY_SUPPLEMENT
Combination Vitamin B1,B6,B12
DIETARY_SUPPLEMENT
Locations 1
Malaysia (1)
Hospital Pakar Universiti Sains Malaysia
Kubang Kerian , Kelantan
NURHAKIM BIN IBRAHIM, MEDICAL OFFICER
Technical details
Status
Recruiting
Phase
Not applicable
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Healthy volunteers
No
Start date
08.12.2025
Completion date
31.01.2027
Registry ID
NCT07312123
Source
clinicaltrials.gov
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