Quality of Life and Functional Outcomes in Laryngeal Cancer Patients

Laryngeal squamous cell carcinomas are head and neck malignancies that directly affect both swallowing and voice functions and are associated with a significant deterioration in patients' quality of life throughout the treatment process. The aim of this study is to evaluate quality of life, voice and swallowing functions, pain, anxiety-depression levels, and patient satisfaction at the pre-treatment period and at the 3rd, 6th, and 12th months post-treatment in patients with laryngeal malignancies, using validated questionnaires, in order to: Elucidate the course of functional recovery following treatment, Individualize rehabilitation and follow-up strategies, and Examine the relationship between functional outcomes and oncological survival.

Inclusion Criteria: * Age ≥ 18 years at the time of enrollment. * Histopathologically confirmed diagnosis of laryngeal squamous cell carcinoma. * Planned to undergo surgical treatment or radiotherapy/chemoradiotherapy as part of standard oncological care. * Willing and able to participate in the study and to provide written informed consent. * No history of psychiatric or neurological disorders that could impair comprehension, questionnaire completion, or study participation. Exclusion Criteria: * Age \< 18 years. * Presence of comorbid conditions that may independently affect swallowing or voice functions. * Patients who withdraw consent or request to discontinue participation during or after the treatment period. * History of psychiatric disorders or use of psychiatric medications that may interfere with study participation or completion of patient-reported outcome measures.