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Not yet recruiting Not applicable NCT07384130

Oral Probiotics for Halitosis in Healthy Adults

No applicable phase (e.g. observational)
Conditions: Halitosis

Sponsor: John Hale

trial.available_in: БГ
Overview
The aim of this study is to evaluate efficacy of a probiotic lozenge containing BLIS M18, BLIS K12 and a prebiotic in healthy adults.
Description
This is a double-blind, randomized controlled colonization pilot study with no crossover to evaluate the efficacy of probiotic lozenges on halitosis in healthy adults. Participants will be randomly assigned to 2 groups consuming probiotic lozenge containing Streptococcus salivarius M18 and K12 and with prebiotic over a 13 day period. Breath scores will be measured at predetermined time points pre and post intervention.
Who can participate
Inclusion Criteria: * Participants should be otherwise healthy, * practice good oral hygiene, * 18 - 70 years of age Exclusion Criteria: * on antibiotic therapy, * immunocompromised (have a weakened immune system) * history of autoimmune disease, * allergy or sensitivity to dairy, * have an active periodontal disease, any known allergy or sensitivity to components of the test product or cysteine solution.
Locations 1
New Zealand (1)
Blis Technologies Ltd
Dunedin , Otago
Technical details
Status
Not yet recruiting
Phase
Not applicable
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Maximum age
70 Years
Healthy volunteers
No
Start date
15.03.2026
Completion date
15.07.2026
Registry ID
NCT07384130
Source
anzctr
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