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Not yet recruiting Not applicable NCT07536464

PEEP Strategies and Mechanical Power in Robotic Surgery

No applicable phase (e.g. observational)
Conditions: Postoperative Pulmonary Complications Impaired Oxygenation Mechanical Ventilation

Sponsor: Ankara City Hospital Bilkent

trial.available_in: БГ
Overview
Robotic surgery requires pneumoperitoneum and steep Trendelenburg positioning, which significantly impair respiratory mechanics and increase the risk of postoperative pulmonary complications. Positive end-expiratory pressure (PEEP) is a key determinant of lung recruitment; however, fixed PEEP strategies may not be optimal for all patients. Individualized PEEP titration strategies, including incremental and decremental approaches, may better optimize lung mechanics. This randomized controlled trial aims to compare the effects of incremental, decremental, and fixed PEEP strategies on cumulative mechanical power (MP-AUC) and postoperative oxygenation in patients undergoing robotic surgery.
Who can participate
Inclusion Criteria: * Age\>= 18 * ASA I-III * Elective robotic surgery Exclusion Criteria: * COPD GOLD ≥2 * Restrictive lung disease * BMI \>40 kg/m² * Heart failure * Preoperative oxygen requirement * Need for postoperative mechanical ventilation * Refusal to participate
Interventions
Fixed PEEP Ventilation
PROCEDURE
Decremental PEEP Strategy
PROCEDURE
Incremental PEEP Strategy
PROCEDURE
Locations

Location information is not available.

Technical details
Status
Not yet recruiting
Phase
Not applicable
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
18 Years
Healthy volunteers
No
Start date
15.04.2026
Completion date
30.06.2026
Registry ID
NCT07536464
Source
clinicaltrials.gov
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