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Active (not recruiting) Not applicable NCT07537920

Trans-septal Quilting Suturing vs Intranasal Silicone Splinting in Septoplasty

No applicable phase (e.g. observational)
Conditions: DNS

Sponsor: Shahida Islam Medical Complex

trial.available_in: БГ
Overview
There is currently little data comparing intranasal silicone splinting versus trans-septal quilted suturing in terms of preventing problems following septoplasty. The purpose of this study is to compare the results of intranasal silicone splinting with trans-septal quilted suturing following septoplasty. After septoplasty, this study will give us a better procedure with fewer adverse effects. Based on the outcomes, this can then regularly be used that specific approach in general practice to treat these specific individuals in an effort to lower their morbidity
Description
With its essential physiological roles, the human nasal cavity has developed over millennia to warm, filter, and humidify breathed air while also promoting olfactory perception and immunological defense. Structural nasal obstruction can result from structural anomalies in the nasal cavity that alter airflow dynamics and raise nasal resistance. The ventilation, temperature control, and humidification processes of the nasal cavity are all negatively impacted by this disease. Numerous studies have demonstrated the positive results of septoplasty, a commonly used surgical procedure for a symptomatic deviated nasal septum. Notably, septoplasty is superior to nonsurgical therapy in reducing nasal obstruction in people with septal deviation, according to a randomized controlled trial. Although the surgical techniques used in this surgery vary, the deviated cartilage and bony septum that provide a dead area between the mucosal flaps are usually removed. Although they are uncommon, post-operative problems such adhesions, perforation, and septal hematoma and the resulting abscess formation might happen. Three primary strategies have been used to avoid these issues. These include transseptal quilted suturing, intranasal silicon splinting, and intranasal occlusive packing. There is currently no evidence to support the use of intranasal occlusive packing because research has not shown that it affects the incidence of problems during septoplasty. For cartilage support, intranasal silicone splinting is quick, easy to perform, and technically straightforward. However, there is a chance of bacterial colonization and discomfort from frequent sneezing and epiphora. Quilting suture, on the other hand, is more widely accessible and better received by patients. Although it is more time-consuming and technically challenging, it can maintain the remaining cartilage and aid in the repair of mucosal tears.
Who can participate
Inclusion Criteria: * All patients between the ages of 10 and 40 who are having septoplasty for a symptomatic nasal septum deviation identified by anterior rhinoscopy; Exclusion Criteria: * Patients who have had nasal surgery in the past. * Individuals who suffer from bleeding disorders (INR \>1.2). * Individuals with co-occurring disorders such as hypertension and diabetes mellitus (based on medical records and history). * Individuals with chronic liver disease, as determined by history and s/bilirubin levels greater than 1.0 mg/dl
Interventions
trans-septal quilting suturing
PROCEDURE
intranasal silicone splinting
PROCEDURE
Locations 1
Pakistan (1)
Sheikh Zayed Hospital
Lahore , Punjab Province
Technical details
Status
Active (not recruiting)
Phase
Not applicable
Study type
INTERVENTIONAL
Sex
Male and female
Minimum age
10 Years
Maximum age
40 Years
Healthy volunteers
No
Start date
04.03.2026
Completion date
03.06.2026
Registry ID
NCT07537920
Source
clinicaltrials.gov
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